General Seek 2 Know

What is genetic testing?

Genetic testing is the process by which we isolate and examine DNA from a patient’s saliva sample. Within DNA, we look at a person’s genes.

What are genes?

Genes are instructions to tell our bodies how to build, maintain, and function throughout our lives. Genetic testing allows us to look at certain genes to determine if the instructions are written properly or not. This information can help us diagnose a disorder or give risks for developing a disorder such as FH or Celiac disease.

What are DNA Variants?

When we do a genetic test, we compare a person’s genes to average genes from many other people. Differences between the person’s genes and the average genes are called variants. All people have many DNA variants. DNA variants usually have little or no impact on a person’s health. Occasionally, DNA variants may cause disease.

What are proteins?

Proteins made by the body are different than the protein we eat in our diet. Proteins are made using the instructions in DNA and are important to the structure, function, and regulation of the body’s organs and tissues.

What does familial mean?

Familial is a term that refers to a condition that is inherited, or passed down through generations in a family, through their DNA.

Testing Test Tube

How does this testing process work?

First, you register online and complete a consent form. Afterwards, a doctor will review your information and determine whether this test is right for you. If testing is indicated, we will charge your credit card and mail you a testing kit. You return the kit to us and the test can begin. Once testing is complete, the doctor will review the results and we will notify you that results are available.

Do I need a doctor to order my testing?

All orders and information submitted are reviewed by a physician from an independent physician network, PWNHealth. Once testing is approved by a PWNHealth physician, we will send you a testing kit. Typically, once you submit your online request for testing, you will receive an email in 1-2 days on whether or not your request was approved. If the independent physician network has any questions they may reach out to you directly.

How long will testing take?

Once you complete the questions and test order request, your request will be reviewed and approved by a PWNHealth physician within 1-2 business days. When your testing is approved, you will be notified by email that a testing kit will be sent. You will provide a saliva sample and return the kit by mail using the included shipping forms. Once the kit arrives at the laboratory, this test takes about 21 days to complete.

How will I receive my results?

Depending on your results, and the review of your personal and family history, some results are delivered by phone through the independent physician group, PWNHealth. Other results are available through the online portal. Once your testing is completed you will be informed that your results are ready and how to receive them.

What kind of kit is needed?

Testing is performed using a saliva specimen. Once your testing order is approved, we will mail you a saliva kit with detailed instructions.

What if my saliva does not work?

Rarely we might have technical problems with your testing. If that happens, we may contact you via email to request a second saliva specimen. That second kit will be sent for no additional charge.

What is an independent physician network?

An independent physician network is a group of qualified healthcare providers who are not directly associated with the testing laboratory.

Where is my test performed?

All Seq2Know tests are performed at an accredited DNA testing laboratory, PreventionGenetics. PreventionGenetics was founded in 2004 and is located in Marshfield, WI.

How long will it take for the doctor to approve my order?

Most orders are approved within 1-2 business days. PreventionGenetics will notify you via email when your order is approved.

Privacy Lock

Who has access to my results?

PreventionGenetics and our Independent Physician Network, PWNHealth, will have access to your results. We will not release any identifiable patient data to anyone other than the ordering doctor, genetic counselor, and other staff involved in the test review process without your documented consent. Your results will not be sent to your insurance company, employer, or others without your written consent.

Are my results kept confidential?

Yes. We take confidentiality and patient privacy very seriously. We follow confidentiality laws related to protected health information and are a government certified laboratory.

Does PreventionGenetics share my information or test results with any researchers or others?

We will not release any identifiable patient data to anyone other than the contracted ordering doctor, genetic counselor, and other staff involved in the test review process at the independent physician network without documented patient consent.

What about genetic discrimination?

The Federal Genetic Information Non-Discrimination Act, also known as GINA, is a law set in place to protect you from employers and health insurers using your genetic information against you. It should be noted the law does not protect against long-term, life, and disability insurers from asking for and using your genetic information in making coverage decisions. Visit for more information.

Support Computer

If you have questions about the testing or how to interpret the results, please contact PWNHealth, the independent provider network that placed your order, by phone: 888-494-7333 or email:

If you have questions about kits, sample collection, or testing status, please email us at

Payment Money Hand

When is my credit card charged?

Your credit card will be charged, and a testing kit will be mailed to your address after testing is determined to be appropriate by a doctor at an Independent Physician Nework, PWNHealth. We will notify you by email when your testing order has been approved and a kit has been sent.

Do you ever cancel testing?

Once your testing order is approved by the independent physician network, the order is valid for 6 months. After 6 months, if we have not received your saliva sample, testing will be cancelled.

Will I have to pay for cancelled testing?

If you do not return the kit within 6 months, we will not refund testing. We will, however, refund your money if testing is cancelled for technical problems in the laboratory.